Significant expression of IGFBP2 in breast cancer compared with benign lesions
نویسندگان
چکیده
منابع مشابه
Significant expression of IGFBP2 in breast cancer compared with benign lesions.
BACKGROUND/AIM Insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) play a role in the normal development of breast tissue, and possibly in breast cancer aetiology. IGFBP2, one of six members of the IGFBP superfamily, acts as regulator of the IGFs and has pleiotropic effects in normal and neoplastic tissues. Because IGFs have mitogenic effects on mammary epithelia, this study in...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2005
ISSN: 0021-9746
DOI: 10.1136/jcp.2004.020834